Ukrainica Bioorganica Acta (UBA) is an open-source journal of bioorganic chemistry. The UBA articles are available for free due to Otava, Ltd sponsorship.
Otava, Ltd was established in 1997 as a subdivision of the Institute of Molecular Biology and Genetics (NAS of Ukraine) and focused on the synthesis and supply of high-quality novel organic compounds on a non-exclusive basis. Now it is a creative, dynamic and privately held company that specializes in drug discovery technologies, custom synthesis and development of fluorescent dyes for biomedical research.
Otava’s products and services are:
KINASE ProHit COMPOUND SETS
OTAVA offers unique ProHit compounds displaying inhibitory activity
(< 1µM for the most active compounds) against distinct protein kinases. The compounds of each Kinase ProHit set are free of Intellectual property and belong to the single chemical class. ProHit compound sets can be used in the development of drugs targeting protein kinase enzymes.
TARGET-FOCUSED LIBRARIES
OTAVA, Ltd. offers unique Receptor-Based Target-Focused libraries. These libraries are created from an extensive compound stock collection (490,000 compounds) and a rigorous process of refinement that involves harnessing the most current methods of theoretical medicinal chemistry. OTAVA's Receptor-Based Target-Focused libraries are generated through Sharp Focusing approach: each molecule's interaction is measured with only a single target in a protein family.
CUSTOM SYNTHESIS SERVICES
OTAVA has extensive experience in the synthesis of highly valuable products for biotech and pharmaceutical applications around the world, including custom synthesis on the basis of rare scaffolds.
OFF-THE-SHELF BUILDING BLOCKS
Otava offers more than 40,000 Building Blocks in multi-gram quantities and purity higher than 95%. These diverse compounds could be used for high-throughput and combinatorial synthesis of pharmaceutical libraries or scale-up of lead compounds for further development.
IN-HOUSE STOCK COMPOUNDS FOR PROMPT DELIVERY
Otava’s In-house Stock Collection contains about 100,000 compounds and ALL compounds have undergone quality control to confirm their chemical structures. All compounds are for prompt delivery.
DRUG-LIKE GREEN COLLECTION
The Green Collection compound library (about 70,000 compounds total) was prepared on the basis of In-house Stock library and pre-formatted by Lipinski’s Rules of Five.
FLUORESCENT DYES
Otava specializes in development and preparing of fluorescent dyes mainly used in life sciences: Cell Biology, Biochemistry, Molecular Biology and Neuroscience. Years of experience enables us to serve our customers with products of excellent high quality at very competitive price level.
CONTRACT RESEARCH
Contract research is one of the main activities of OTAVA. Many leading pharmaceutical and chemical companies choose OTAVA as a reliable partner for collaboration in research and development of high-tech products.
Contact Information:
OTAVA
P.O. Box 88
Kyiv 187,
03187 Ukraine
Fax: 1-866-881-9921
info@otavachemicals.com
mailotava@gmail.com
OTAVA – North American Division
55 Ellerslie Ave.,
Suite 524
Toronto, ON M2N 1X9 Canada
Tel.: 1-416-305-9979
Fax: 1-866-881-9921
(Toll-free in US & Canada)
north.america@otavachemicals.com
